The full title of the book is Evil genes : why Rome fell, Hitler rose, Enron failed and my sister stole my mother's boyfriend by Barbara Oakley. Although she deals with some genetic research, this is primarily an overview of the research on the neurophysiology and neurochemistry of various psychiatric disorders. Personal anecdotes are sprinkled throughout as her interest in the area did come from her puzzlement over her sister's often amoral and Machiavellian behavior. She focuses initially on the development of the construct of Machiavelliamism and then moves on to its relationship to various personality disorders, e.g., narcissistic, borderline, sociopathic and psychopathic disorders. She has separate chapters on Mao Zedong, Adolf Hitler, and Slobodan Milosevic. She posits that some personality disorders may actually be adaptive, helping certain people rise to the top and gain the power and influence to expand their gene pool. She has lots of interesting side notes on things like the neurobiology of religiosity and political beliefs. Her background is as a systems engineer and she does a reasonably good job of bringing some diverse areas of research together, but it is dense and technical reading and I wouldn't recommend it unless you yourself feel compelled to learn more about someone you think might be personality disordered. Her conclusions are that people really are determined more by inheritance than nurture--undoubtedly a comfort to parents/family of those with serious personality disorders. And so I am reminded that people do not change awfully much, and that wishing they would behave differently is just that--wishing.
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